You should talk with your doctor about any questions you have and to understand the potential side effects and benefits of any medication. This is not a comprehensive list of all possible side effects. 1, 2, 3ĭisclaimer: All medications, including Zoloft, can cause side effects that can be mild or serious. If Zoloft makes you drowsy, then taking it in the morning can make the side effect noticeable. Higher doses are more likely to cause drowsiness. Lastly, the dosage and timing of Zoloft can be a reason why some become lethargic on this medication. Each person’s experience with side effects is different given that each person has differing genetic and physical characteristics. With the change in serotonin levels, it may impact the sleep-wake cycle and lead to drowsiness or sedation in some individuals.Īnother consideration would be the individual factors of the person taking Zoloft. One reason could be that Zoloft works by increasing the level of serotonin which is a chemical involved with mood regulation as well as sleep regulation.

The exact reason why Zoloft causes sleepiness isn’t known, but there are theories. 4, 5 If symptoms persist or worsen, speak with your physician about what changes can be made to your therapy. These often improve over the first week or two of therapy. Side effects typically are mild at the start of treatment, but generally improve with time. These changes can result in a person feeling tired or fatigued. Zoloft may also cause manic episodes, a side effect for people who have bipolar disorder, where symptoms may include greatly increased energy and severe trouble sleeping. Changes in sleep habits are common side effects of Zoloft, and can cause increased sleepiness or insomnia.

Sleep aids for zoloft insomnia